The Effects of S-Carboxymethylcysteine and N-Acetylcysteine on the Adherence of Moraxella catarrhalis to Human Pharyngeal Epithelial Cells

We investigated the effects of two mucoregulating drugs, S-carboxymethylcysteine (S-CMC) and N-acetylcysteine (NAC), on the attachment of Moraxella catarrhalis (M. catarrhalis) to pharyngeal epithelial cells. The attachment of M. catarrhalis decreased (33-57%) significantly (P

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Veröffentlicht in:	MICROBIOLOGY and IMMUNOLOGY 1999, Vol.43(2), pp.107-113
Hauptverfasser:	Zheng, Can Hong, Ahmed, Kamruddin, Rikitomi, Naoto, Martinez, Glenda, Nagatake, Tsuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcysteine - pharmacology Adult Aged Asthma - pathology Attachment Bacterial Adhesion - drug effects Bacteriology Biological and medical sciences Bronchiectasis - pathology Bronchitis - pathology Carbocysteine - metabolism Carbocysteine - pharmacology Cells Epithelial Cells - drug effects Epithelial Cells - microbiology Epithelial Cells - ultrastructure Expectorants - pharmacology Female Fundamental and applied biological sciences. Psychology Humans Male Microbiology Middle Aged Moraxella (Branhamella) catarrhalis - drug effects Moraxella (Branhamella) catarrhalis - physiology Moraxella catarrhalis N-acetylcysteine Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Pharynx - cytology Pharynx - microbiology Pulmonary Emphysema - pathology S-carboxymethylcysteine Sputum - metabolism
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Beschreibung
Zusammenfassung:	We investigated the effects of two mucoregulating drugs, S-carboxymethylcysteine (S-CMC) and N-acetylcysteine (NAC), on the attachment of Moraxella catarrhalis (M. catarrhalis) to pharyngeal epithelial cells. The attachment of M. catarrhalis decreased (33-57%) significantly (P
ISSN:	0385-5600 1348-0421
DOI:	10.1111/j.1348-0421.1999.tb02381.x