Testicular Seminoma in a Patient with Ataxia-Telangiectasia

Testicular Seminoma in a Patient with Ataxia-Telangiectasia

The case history of a 27-year-old man with ataxia-telangiectasia (AT) and testicular seminoma is reported. This is the first documented description of such a malignancy in AT, a syndrome associated with a markedly increased risk of malignant disease. Furthermore, alpha-foetoprotein levels have limit...

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Veröffentlicht in:Clinical oncology (Royal College of Radiologists (Great Britain)) 1999-01, Vol.11 (1), p.63-64
Hauptverfasser: Phillips, H.A., Howard, G.C.W.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
alpha-Fetoproteins - analysis
Alpha-foetoprotein
Ataxia Telangiectasia - complications
Ataxia-telangiectasia
Biological and medical sciences
Diagnosis, Differential
Gynecology. Andrology. Obstetrics
Humans
Male
Male genital diseases
Medical sciences
Seminoma
Seminoma - complications
Seminoma - diagnosis
Seminoma - pathology
Seminoma - surgery
Testicular Neoplasms - complications
Testicular Neoplasms - diagnosis
Testicular Neoplasms - pathology
Testicular Neoplasms - surgery
Testis
Tumors
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Beschreibung
Zusammenfassung:The case history of a 27-year-old man with ataxia-telangiectasia (AT) and testicular seminoma is reported. This is the first documented description of such a malignancy in AT, a syndrome associated with a markedly increased risk of malignant disease. Furthermore, alpha-foetoprotein levels have limitations as a tumour marker in this situation because serum levels may be elevated as a biochemical manifestation of AT.
ISSN:0936-6555
1433-2981
DOI:10.1053/clon.1999.9013