Ramipril reduces QT dispersion in patients with acute myocardial infarction and heart failure

In a cohort of 67 patients from the Acute Infarction Ramipril Efficacy study, we showed that ramipril therapy was associated with a significant reduction in QT dispersion over a 2-month period after acute myocardial infarction. This reduction of ventricular repolarization inhomogeneity indicates an...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The American journal of cardiology 1999-03, Vol.83 (6), p.969-971
Hauptverfasser:	Spargias, Konstantinos S., Lindsay, Steven J., Hall, Alistair S., Cowan, J.Campbell, Ball, Stephen G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - therapeutic use Biological and medical sciences Cardiology Cardiovascular system Drug therapy Electrocardiography - drug effects Female Heart attacks Heart failure Heart Failure - etiology Humans Male Medical sciences Middle Aged Myocardial Infarction - complications Myocardial Infarction - drug therapy Myocardial Infarction - physiopathology Pharmacology. Drug treatments Ramipril - therapeutic use Single-Blind Method Vasodilator agents. Cerebral vasodilators
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	In a cohort of 67 patients from the Acute Infarction Ramipril Efficacy study, we showed that ramipril therapy was associated with a significant reduction in QT dispersion over a 2-month period after acute myocardial infarction. This reduction of ventricular repolarization inhomogeneity indicates an antiarrhythmic effect and may be an important additional mechanism for the reduced all-cause mortality and sudden death incidence achieved with angiotensin-converting enzyme inhibition after acute myocardial infarction.
ISSN:	0002-9149 1879-1913
DOI:	10.1016/S0002-9149(98)01049-2