Oxidative stress intensity in lens and aqueous depending on age-related cataract type and brunescense

Cataract formation represents a serious problem in the elderly, and has a large impact on healthcare budget. The oxidative stress form and intensity might determine the cataract type and pigmentation, making efforts in the cataract prevention challenge more complex. This is a retrospective cross-sec...

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Veröffentlicht in:European journal of ophthalmology 2008-09, Vol.18 (5), p.669-674
Hauptverfasser: Zoric, L, Elek-Vlajic, S, Jovanovic, M, Kisic, B, Djokic, O, Canadanovic, V, Cosic, V, Jaksic, V
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Sprache:eng
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Zusammenfassung:Cataract formation represents a serious problem in the elderly, and has a large impact on healthcare budget. The oxidative stress form and intensity might determine the cataract type and pigmentation, making efforts in the cataract prevention challenge more complex. This is a retrospective cross-sectional review of 80 samples of aqueous humor and lens corticonuclear blocks. Aqueous samples were analyzed by the method of antioxidant activity estimation (%iMDA), while lipid peroxides (LP) and total sulfhydryl groups (TSH) were determined in lenses. Mixed and brunescent cataracts have statistically significant lower values of antioxidative %iMDA and TSH (p
ISSN:1120-6721
1724-6016
DOI:10.1177/112067210801800501