Prevalence and Clinical Characteristics of HIV Type 1-Infected Patients Receiving Dialysis in Spain : Results of a Spanish Survey in 2006: GESIDA 48/05 Study

End-stage renal diseases (ESRD) are becoming more frequent in HIV-infected patients. In Europe there is little information about HIV-infected patients on dialysis. A cross-sectional multicenter survey in 328 Spanish dialysis units was conducted in 2006. Information from 14,876 patients in dialysis w...

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Veröffentlicht in:AIDS research and human retroviruses 2008-10, Vol.24 (10), p.1229-1235
Hauptverfasser: TRULLAS, J.-C, BARRIL, G, MOLINA, J, MARTINEZ-CASTELAO, A, GONZALEZ-GARCIA, J, MIRO, J.-M, COFAN, F, MORENO, A, CASES, A, FERNANDEZ-LUCAS, M, MARTINEZ-ARA, J, CEBALLOS, M, GARCIA-DE-DIEGO, J, MUNIZ, M.-L
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Sprache:eng
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Zusammenfassung:End-stage renal diseases (ESRD) are becoming more frequent in HIV-infected patients. In Europe there is little information about HIV-infected patients on dialysis. A cross-sectional multicenter survey in 328 Spanish dialysis units was conducted in 2006. Information from 14,876 patients in dialysis was obtained (81.6% of the Spanish dialysis population). Eighty-one were HIV infected (0.54%; 95% CI, 0.43-0.67), 60 were on hemodialysis, and 21 were on peritoneal dialysis. The mean (range) age was 45 (28-73) years. Seventy-two percent were men and 33% were former drug users. The mean (range) time of HIV infection was 11 (1-27) years and time on dialysis was 4.6 (0.4-25) years. ESRD was due to glomerulonephritis (36%) and diabetes (15%). HIV-associated nephropathy was not reported. Eighty-five percent were on HAART, 76.5% had a CD4 T cell count above 200 cells, and 73% had undetectable viral load. Thirty-nine percent of patients met criteria for inclusion on the renal transplant (RT) waiting list but only 12% were included. Sixty-one percent had HCV coinfection. HCV-coinfected patients had a longer history of HIV, more previous AIDS events, parenteral transmission as the most common risk factor for acquiring HIV infection, and less access to the RT waiting list (p < 0.05). The prevalence of HIV infection in Spanish dialysis units in 2006 was 0.54% HCV coinfection was very frequent (61%) and the percentage of patients included on the Spanish RT waiting list was low (12%).
ISSN:0889-2229
1931-8405
DOI:10.1089/aid.2008.0158