WNT targets: repression and activation

Several puzzling observations made previously suggested that target genes that are activated by WNT signaling during development were actively repressed in the absence of the signal. Recent work sheds light on how this switch between repression and activation is regulated.

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Trends in genetics 1999, Vol.15 (1), p.1-3
1. Verfasser:	Nusse, Roel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Caenorhabditis elegans - embryology Caenorhabditis elegans - genetics Classical genetics, quantitative genetics, hybrids Drosophila melanogaster - embryology Drosophila melanogaster - genetics Drosophila Proteins Embryonic Development Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental - genetics Gene Expression Regulation, Developmental - physiology Genetics of eukaryotes. Biological and molecular evolution Helminth Proteins - genetics Helminth Proteins - physiology Insect Proteins - genetics Insect Proteins - physiology Invertebrata Models, Genetic Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins - physiology Repressor Proteins - genetics Repressor Proteins - physiology signal transduction Signal Transduction - physiology transcription Transcription Factors - physiology Wnt Wnt Proteins Xenopus laevis - embryology Xenopus laevis - growth & development Zebrafish Proteins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Several puzzling observations made previously suggested that target genes that are activated by WNT signaling during development were actively repressed in the absence of the signal. Recent work sheds light on how this switch between repression and activation is regulated.
ISSN:	0168-9525
DOI:	10.1016/S0168-9525(98)01634-5