Selegiline augmentation of antipsychotics for the treatment of negative symptoms in schizophrenia

This case series describes three patients with a DSM-IV diagnosis of schizophrenia attending a continuing day treatment (CDT) program. They showed significant improvement in negative symptoms and overall functioning after the addition of selegiline to the antipsychotic regimen. No side effects were...

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Veröffentlicht in:	Comprehensive psychiatry 1999-03, Vol.40 (2), p.148-150
Hauptverfasser:	Gupta, Sanjay, Droney, Thomas, Kyser, Alan, Keller, Peggy
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antipsychotic Agents - therapeutic use Biological and medical sciences Brief Psychiatric Rating Scale Female Humans Male Medical sciences Middle Aged Monoamine Oxidase Inhibitors - therapeutic use Neuropharmacology Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Psychotic Disorders - drug therapy Psychotic Disorders - etiology Schizophrenia - complications Schizophrenia - diagnosis Schizophrenic Psychology Selegiline - therapeutic use
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Beschreibung
Zusammenfassung:	This case series describes three patients with a DSM-IV diagnosis of schizophrenia attending a continuing day treatment (CDT) program. They showed significant improvement in negative symptoms and overall functioning after the addition of selegiline to the antipsychotic regimen. No side effects were observed with this combination.
ISSN:	0010-440X 1532-8384
DOI:	10.1016/S0010-440X(99)90119-0