Pancreatic Stellate Cells and Pancreatic Cancer Cells : An Unholy Alliance

Pancreatic cancer--a tumor displaying a particularly abundant stromal reaction--is notorious for its poor prognosis. Recent studies, via newly developed orthotopic models, provide compelling evidence of an important role for pancreatic stellate cells (PSC) in pancreatic cancer progression. Character...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2008-10, Vol.68 (19), p.7707-7710
Hauptverfasser:	VONLAUFEN, Alain, PHILLIPS, Phoebe A, ZHIHONG XU, GOLDSTEIN, David, PIROLA, Romano C, WILSON, Jeremy S, APTE, Minoti V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Biological and medical sciences Cell Proliferation Disease Progression Gastroenterology. Liver. Pancreas. Abdomen Humans Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Models, Biological Pancreas - cytology Pancreas - physiology Pancreatic Neoplasms - etiology Pancreatic Neoplasms - pathology Pharmacology. Drug treatments Stromal Cells - physiology Tumors
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