trans-2-Aminocyclohexanol as a pH-sensitive conformational switch in lipid amphiphiles

trans-2-Aminocyclohexanol as a pH-sensitive conformational switch in lipid amphiphiles

Protonation-induced conformational change of lipid tails is reported as a novel strategy to render pH-sensitive lipid amphiphiles and lipid colloids.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2008-01 (39), p.4774-4776
Hauptverfasser: Brazdova, Barbora, Zhang, Ningrong, Samoshin, Vyacheslav V, Guo, Xin
Format: Artikel
Sprache:eng
Schlagworte:
Colloids - chemistry
Cyclohexanols - chemistry
Hydrogen-Ion Concentration
Lipids - chemistry
Liposomes - chemistry
Molecular Conformation
Protons
Stereoisomerism
Surface-Active Agents - chemistry
Time Factors
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Zusammenfassung:Protonation-induced conformational change of lipid tails is reported as a novel strategy to render pH-sensitive lipid amphiphiles and lipid colloids.
ISSN:1359-7345
1364-548X
DOI:10.1039/b807704e