Hemoglobin and red cell indices correlated with serum ferritin concentration in late pregnancy
Objective: To study the correlation between third-trimester serum ferritin concentration and hemoglobin and red cell indices to select the best hematologic characteristic to identify women who need iron therapy. Methods: In a prospective study, blood was drawn from pregnant women with hemoglobin abo...
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Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1999-03, Vol.93 (3), p.427-431 |
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creator | Tam, Kar-Fai Lao, Terence T |
description | Objective: To study the correlation between third-trimester serum ferritin concentration and hemoglobin and red cell indices to select the best hematologic characteristic to identify women who need iron therapy.
Methods: In a prospective study, blood was drawn from pregnant women with hemoglobin above 10 g/dL, and thalassemia trait excluded at booking, at 28–30 weeks’ gestation to study the correlation (Spearman ρ value) between serum ferritin concentration and hemoglobin level, mean corpuscular volume, mean cell hemoglobin, mean cell hemoglobin concentration, and hematocrit. The best relationship was identified using receiver operating characteristic (ROC) curves.
Results: Serum ferritin concentration correlated significantly with hemoglobin (ρ = .211), mean corpuscular volume (ρ = .332), mean cell hemoglobin (ρ = .304), and hematocrit (ρ = .199). The area under the ROC curve was largest for hemoglobin.
Conclusion: Serum ferritin concentration at the early third trimester correlated best with hemoglobin level. If a hemoglobin level of 11 g/dL or below (25% of all patients) was used as the cutoff, 64% of women who needed iron therapy were identified. |
doi_str_mv | 10.1016/S0029-7844(98)00422-0 |
format | Article |
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Methods: In a prospective study, blood was drawn from pregnant women with hemoglobin above 10 g/dL, and thalassemia trait excluded at booking, at 28–30 weeks’ gestation to study the correlation (Spearman ρ value) between serum ferritin concentration and hemoglobin level, mean corpuscular volume, mean cell hemoglobin, mean cell hemoglobin concentration, and hematocrit. The best relationship was identified using receiver operating characteristic (ROC) curves.
Results: Serum ferritin concentration correlated significantly with hemoglobin (ρ = .211), mean corpuscular volume (ρ = .332), mean cell hemoglobin (ρ = .304), and hematocrit (ρ = .199). The area under the ROC curve was largest for hemoglobin.
Conclusion: Serum ferritin concentration at the early third trimester correlated best with hemoglobin level. If a hemoglobin level of 11 g/dL or below (25% of all patients) was used as the cutoff, 64% of women who needed iron therapy were identified.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>DOI: 10.1016/S0029-7844(98)00422-0</identifier><identifier>PMID: 10074993</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Biological and medical sciences ; Erythrocyte Indices ; Erythrocytes - chemistry ; Female ; Ferritins - blood ; Gynecology. Andrology. Obstetrics ; Hematocrit ; Hemoglobins - analysis ; Humans ; Management. Prenatal diagnosis ; Medical sciences ; Pregnancy ; Pregnancy Trimester, Third ; Pregnancy. Fetus. Placenta ; Prospective Studies ; ROC Curve</subject><ispartof>Obstetrics and gynecology (New York. 1953), 1999-03, Vol.93 (3), p.427-431</ispartof><rights>1999 The American College of Obstetricians and Gynecologists</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4353-b02b562ad0fe6126220968c7a3efa12b1812aceee446559f2b251e5f4c5f77953</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1701003$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10074993$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tam, Kar-Fai</creatorcontrib><creatorcontrib>Lao, Terence T</creatorcontrib><title>Hemoglobin and red cell indices correlated with serum ferritin concentration in late pregnancy</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>Objective: To study the correlation between third-trimester serum ferritin concentration and hemoglobin and red cell indices to select the best hematologic characteristic to identify women who need iron therapy.
Methods: In a prospective study, blood was drawn from pregnant women with hemoglobin above 10 g/dL, and thalassemia trait excluded at booking, at 28–30 weeks’ gestation to study the correlation (Spearman ρ value) between serum ferritin concentration and hemoglobin level, mean corpuscular volume, mean cell hemoglobin, mean cell hemoglobin concentration, and hematocrit. The best relationship was identified using receiver operating characteristic (ROC) curves.
Results: Serum ferritin concentration correlated significantly with hemoglobin (ρ = .211), mean corpuscular volume (ρ = .332), mean cell hemoglobin (ρ = .304), and hematocrit (ρ = .199). The area under the ROC curve was largest for hemoglobin.
Conclusion: Serum ferritin concentration at the early third trimester correlated best with hemoglobin level. If a hemoglobin level of 11 g/dL or below (25% of all patients) was used as the cutoff, 64% of women who needed iron therapy were identified.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Erythrocyte Indices</subject><subject>Erythrocytes - chemistry</subject><subject>Female</subject><subject>Ferritins - blood</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Hematocrit</subject><subject>Hemoglobins - analysis</subject><subject>Humans</subject><subject>Management. Prenatal diagnosis</subject><subject>Medical sciences</subject><subject>Pregnancy</subject><subject>Pregnancy Trimester, Third</subject><subject>Pregnancy. Fetus. Placenta</subject><subject>Prospective Studies</subject><subject>ROC Curve</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE2L1TAUQIMoznP0JyhdiOiievPVNiuRQR1hwIUKrgxpejMvmjbPpPUx_950-lB3LkJIOCfhHkIeU3hJgTavPgEwVbedEM9V9wJAMFbDHbKjXctrxvnXu2T3BzkjD3L-DlBExe-TMwrQCqX4jny7xDFeh9j7qTLTUCUcKoshVH4avMVc2ZgSBjOX-6Of91XGtIyVw5T8XBwbJ4vTnMzs41SkakWrQ8LryUz25iG550zI-Oi0n5Mv795-vrisrz6-_3Dx5qq2gkte98B62TAzgMOGsoYxUE1nW8PRGcp62lFmLCIK0UipHOuZpCidsNK1rZL8nDzb3j2k-HPBPOvR53UOM2Fcsm5UQ7lUtIByA22KOSd0-pD8aNKNpqDXsPo2rF6radXp27Aaivfk9MHSjzj8Y20lC_D0BJhsTXCpjO_zX66Fgq6Y2LBjDDOm_CMsR0x6jybM-_IbQMMk1FQpBbyc6rLYqr3eNCwRf_liZOuxpB98QjvrIfr_DPAbNxSkxg</recordid><startdate>199903</startdate><enddate>199903</enddate><creator>Tam, Kar-Fai</creator><creator>Lao, Terence T</creator><general>Elsevier Inc</general><general>The American College of Obstetricians and Gynecologists</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199903</creationdate><title>Hemoglobin and red cell indices correlated with serum ferritin concentration in late pregnancy</title><author>Tam, Kar-Fai ; Lao, Terence T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4353-b02b562ad0fe6126220968c7a3efa12b1812aceee446559f2b251e5f4c5f77953</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Erythrocyte Indices</topic><topic>Erythrocytes - chemistry</topic><topic>Female</topic><topic>Ferritins - blood</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Hematocrit</topic><topic>Hemoglobins - analysis</topic><topic>Humans</topic><topic>Management. Prenatal diagnosis</topic><topic>Medical sciences</topic><topic>Pregnancy</topic><topic>Pregnancy Trimester, Third</topic><topic>Pregnancy. Fetus. Placenta</topic><topic>Prospective Studies</topic><topic>ROC Curve</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tam, Kar-Fai</creatorcontrib><creatorcontrib>Lao, Terence T</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tam, Kar-Fai</au><au>Lao, Terence T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hemoglobin and red cell indices correlated with serum ferritin concentration in late pregnancy</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1999-03</date><risdate>1999</risdate><volume>93</volume><issue>3</issue><spage>427</spage><epage>431</epage><pages>427-431</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>Objective: To study the correlation between third-trimester serum ferritin concentration and hemoglobin and red cell indices to select the best hematologic characteristic to identify women who need iron therapy.
Methods: In a prospective study, blood was drawn from pregnant women with hemoglobin above 10 g/dL, and thalassemia trait excluded at booking, at 28–30 weeks’ gestation to study the correlation (Spearman ρ value) between serum ferritin concentration and hemoglobin level, mean corpuscular volume, mean cell hemoglobin, mean cell hemoglobin concentration, and hematocrit. The best relationship was identified using receiver operating characteristic (ROC) curves.
Results: Serum ferritin concentration correlated significantly with hemoglobin (ρ = .211), mean corpuscular volume (ρ = .332), mean cell hemoglobin (ρ = .304), and hematocrit (ρ = .199). The area under the ROC curve was largest for hemoglobin.
Conclusion: Serum ferritin concentration at the early third trimester correlated best with hemoglobin level. If a hemoglobin level of 11 g/dL or below (25% of all patients) was used as the cutoff, 64% of women who needed iron therapy were identified.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>10074993</pmid><doi>10.1016/S0029-7844(98)00422-0</doi><tpages>5</tpages></addata></record> |
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subjects | Adult Biological and medical sciences Erythrocyte Indices Erythrocytes - chemistry Female Ferritins - blood Gynecology. Andrology. Obstetrics Hematocrit Hemoglobins - analysis Humans Management. Prenatal diagnosis Medical sciences Pregnancy Pregnancy Trimester, Third Pregnancy. Fetus. Placenta Prospective Studies ROC Curve |
title | Hemoglobin and red cell indices correlated with serum ferritin concentration in late pregnancy |
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