Haloperoxidases and their role in biotransformation reactions

Haloperoxidases and their role in biotransformation reactions

The past year has seen further structural characterisation of both nonmetal and vanadium haloperoxidase enzymes to add to that already known for the haem- and vanadium-containing enzymes. Exploitation of these enzymes for halogenation, sulfoxidation, epoxidation, oxidation of indoles and other biotr...

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Veröffentlicht in:Current opinion in chemical biology 1999-02, Vol.3 (1), p.28-34
1. Verfasser: Littlechild, Jennifer
Format: Artikel
Sprache:eng
Schlagworte:
Biotransformation
Cloning, Molecular
Halogens - metabolism
Peroxidases - biosynthesis
Peroxidases - metabolism
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Zusammenfassung:The past year has seen further structural characterisation of both nonmetal and vanadium haloperoxidase enzymes to add to that already known for the haem- and vanadium-containing enzymes. Exploitation of these enzymes for halogenation, sulfoxidation, epoxidation, oxidation of indoles and other biotransformations has increased as more information on their catalytic mechanism has been obtained.
ISSN:1367-5931
1879-0402
DOI:10.1016/S1367-5931(99)80006-4