Karyotype Evolution in a Case of Uterine Angioleiomyoma

Clonal karyotypic alterations of a uterine angioleiomyoma of a 41-year-old woman are reported. Cytogenetically a stemline of the tumor and two related subclones with additional abnormalities due to karyotypic evolution were identified: 46,X,t(X;11)(p11.4;p15)/46,idem,inv(2)(p15q13)/46, idem,inv(2)(p...

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Veröffentlicht in:	Cancer genetics and cytogenetics 1999, Vol.108 (1), p.79-80
Hauptverfasser:	Hennig, Yvonne, Caselitz, Jörg, Stern, Corinna, Bartnitzke, Sabine, Bullerdiek, Jörn
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Angiomyoma - genetics Angiomyoma - pathology Angiomyoma - surgery Biological and medical sciences Chromosome Inversion Chromosome Mapping Chromosomes, Human, Pair 11 Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Karyotyping Medical sciences Translocation, Genetic Tumors Uterine Neoplasms - genetics Uterine Neoplasms - pathology Uterine Neoplasms - surgery X Chromosome
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Zusammenfassung:	Clonal karyotypic alterations of a uterine angioleiomyoma of a 41-year-old woman are reported. Cytogenetically a stemline of the tumor and two related subclones with additional abnormalities due to karyotypic evolution were identified: 46,X,t(X;11)(p11.4;p15)/46,idem,inv(2)(p15q13)/46, idem,inv(2)(p15q13),t(5;20)(q13;q13.2). None of the aberrations observed in the present case has been reported in uterine smooth muscle tumors before.
ISSN:	0165-4608 1873-4456
DOI:	10.1016/S0165-4608(98)00123-X