Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy

Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy

Jacquemin et al discuss the possible role of a multidrug resistance 3 (MDR3) gene defect in the pathogenesis of intrahepatic cholestasis of pregnancy.

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Bibliographische Detailangaben
Veröffentlicht in:The Lancet (British edition) 1999-01, Vol.353 (9148), p.210-211
Hauptverfasser: Jacquemin, Emmanuel, Cresteil, Danièle, Manouvrier, Sylvie, Boute, Odile, Hadchouel, Michelle
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Cholestasis, Intrahepatic - genetics
Codon, Terminator
Defects
Female
Frameshift Mutation
Gastroenterology. Liver. Pancreas. Abdomen
Genes, MDR - genetics
Genetics
Heterozygote
Humans
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Medical sciences
Mutation
Other diseases. Semiology
Pathology
Pregnancy
Pregnancy Complications
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Beschreibung
Zusammenfassung:Jacquemin et al discuss the possible role of a multidrug resistance 3 (MDR3) gene defect in the pathogenesis of intrahepatic cholestasis of pregnancy.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(05)77221-4