Mortality in the CHAOS trial

Mortality in the CHAOS trial

Results of the CHAOS trial of alpha-tocopherol showed a 75% decrease in non-fatal myocardial infarction in the alpha-tocopherol group, but apparently no effect on mortality. Mitchinson et al discuss more accurate study of deaths and of compliance.

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Veröffentlicht in:The Lancet (British edition) 1999-01, Vol.353 (9150), p.381-382
Hauptverfasser: Mitchinson, Malcolm J, Stephens, Nigel G, Parsons, Ann, Bligh, Elizabeth, Schofield, Peter M, Brown, Morris J
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Cardiovascular system
Clinical trials
Clinical Trials as Topic
Coronary Artery Disease - drug therapy
Coronary Artery Disease - mortality
Double-Blind Method
Drug therapy
Heart attacks
Humans
Medical sciences
Miscellaneous
Mortality
Myocardial infarction
Myocardial Infarction - mortality
Myocardial Ischemia - mortality
Pharmacology. Drug treatments
Vitamin E - therapeutic use
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Zusammenfassung:Results of the CHAOS trial of alpha-tocopherol showed a 75% decrease in non-fatal myocardial infarction in the alpha-tocopherol group, but apparently no effect on mortality. Mitchinson et al discuss more accurate study of deaths and of compliance.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(05)74955-2