A Case Report of Nephrotic Syndrome Due to Collapsing Focal Segmental Glomerulosclerosis Treated With Low‐density Lipoprotein Apheresis

: We herein report the case of a 73‐year‐old woman with steroid and cyclosporine resistant collapsing focal segmental glomerulosclerosis (FSGS) whose refractory proteinuria and hypoproteinemia were controlled with low‐density lipoprotein apheresis (LDL‐A). She was initially treated with steroid therapy, including methylprednisolone pulse and cyclosporine therapy. However, her hypoproteinemia, accompanied with renal insufficiency, persisted despite these therapies. We treated her using LDL‐A and found improvement in her urine protein excretion, hyperlipidemia, hypoproteinemia, and renal function as a result of this treatment. This suggests that LDL‐A may therefore be an effective therapy for nephrotic syndrome due to collapsing FSGS.