Practical Heck−Mizoroki Coupling Protocol for Challenging Substrates Mediated by an N-Heterocyclic Carbene-Ligated Palladacycle

A highly active, N-heterocyclic carbene-palladacycle precatalyst for the Heck−Mizoroki reaction was rationally designed. The complex can be synthesized on a large scale in excellent yield by a novel, one-pot, three-component reaction and is tolerant to air, moisture, and long-term storage. A wide ra...

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Veröffentlicht in:Organic letters 2008-09, Vol.10 (18), p.3949-3952
Hauptverfasser: Kantchev, Eric Assen B, Peh, Guang-Rong, Zhang, Chi, Ying, Jackie Y
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Sprache:eng
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