Electroacupuncture improves impaired gastric motility and slow waves induced by rectal distension in dogs
Rectal distension (RD) is known to induce upper gastrointestinal (GI) symptoms. The aim of this study was to investigate the effects and underlying mechanisms of RD on gastric slow waves (GSW) and motor activity and furthermore to investigate the effects and mechanisms of electroacupuncture (EA) on...
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Veröffentlicht in: | American journal of physiology: Gastrointestinal and liver physiology 2008-09, Vol.295 (3), p.G614-G620 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Rectal distension (RD) is known to induce upper gastrointestinal (GI) symptoms. The aim of this study was to investigate the effects and underlying mechanisms of RD on gastric slow waves (GSW) and motor activity and furthermore to investigate the effects and mechanisms of electroacupuncture (EA) on GSW and motor activity. Eight female hound dogs chronically implanted with gastric serosal electrodes and a gastric fistula were studied in six separate sessions. Antral motility, GSW, heart rate variability, and rectal pressure were evaluated for the above purposes. 1) RD at a volume of 120 ml suppressed antral motility significantly. Guanethidine blocked the inhibitory effect of RD. EA at ST36 was able to restore the suppressed antral contractions induced by RD (16.6+/-1.7 vs. 8.0+/-1.4, P |
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ISSN: | 0193-1857 1522-1547 |
DOI: | 10.1152/ajpgi.90322.2008 |