HIV-DNA in rectal cells is well correlated with HIV-DNA in blood in different groups of patients, including long-term non-progressors

Most of the body's lymphoid tissue is in gut and constitutes an immense HIV reservoir. We quantified HIV-DNA in rectum and compared it with blood levels for 27 HIV-infected adults from different groups. We observed a large range of rectal and blood HIV-DNA levels. They were positively correlate...

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Veröffentlicht in:AIDS (London) 2008-09, Vol.22 (14), p.1880-1882
Hauptverfasser: AVETTAND-FENOEL, Véronique, PRAZUCK, Thierry, HOCQUELOUX, Laurent, MELARD, Adeline, MICHAU, Christophe, KERDRAON, Rémy, AGOUTE, Eric, ROUZIOUX, Christine
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Sprache:eng
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Zusammenfassung:Most of the body's lymphoid tissue is in gut and constitutes an immense HIV reservoir. We quantified HIV-DNA in rectum and compared it with blood levels for 27 HIV-infected adults from different groups. We observed a large range of rectal and blood HIV-DNA levels. They were positively correlated (r = 0.841, P
ISSN:0269-9370
1473-5571
DOI:10.1097/QAD.0b013e32830fbdbc