Selective oestrogen receptor modulation: molecular pharmacology for the millennium

Knowledge of the mechanism of action and pharmacology of tamoxifen and raloxifene, for the prevention of breast cancer and osteoporosis respectively, has opened the door for the discovery of multifunctional medicines. There is now the potential to prevent osteoporosis, coronary heart disease, breast...

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Veröffentlicht in:	European journal of cancer (1990) 1999-12, Vol.35 (14), p.1974-1985
Hauptverfasser:	Levenson, A.S., Jordan, V.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	breast cancer Breast Neoplasms - prevention & control Female Humans prevention raloxifene Raloxifene Hydrochloride - therapeutic use Selective Estrogen Receptor Modulators - therapeutic use tamoxifen Tamoxifen - therapeutic use
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Knowledge of the mechanism of action and pharmacology of tamoxifen and raloxifene, for the prevention of breast cancer and osteoporosis respectively, has opened the door for the discovery of multifunctional medicines. There is now the potential to prevent osteoporosis, coronary heart disease, breast and endometrial cancer in postmenopausal women with elevated risk factors.
ISSN:	0959-8049 1879-0852
DOI:	10.1016/S0959-8049(99)00297-X