Corrected 17-alpha-hydroxyprogesterone values adjusted by a scoring system for screening congenital adrenal hyperplasia in premature infants

This study investigated the use of corrected 17-alpha-hydroxyprogesterone (17-OHP) values to detect congenital adrenal hyperplasia (CAH) in newborn infants. 17-OHP concentrations in blood spots from 913 neonates were measured using a neonatal screening test. A prematurity index was calculated using...

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Veröffentlicht in:	Annals of clinical and laboratory science 2008-06, Vol.38 (3), p.235-240
Hauptverfasser:	Lee, Ji Eun, Moon, Yeonsook, Lee, Moon Hee, Jun, Yong Hoon, Oh, Kyung Il, Choi, Jong Weon
Format:	Artikel
Sprache:	eng
Schlagworte:	17-alpha-Hydroxyprogesterone - blood Adrenal Hyperplasia, Congenital - blood Adrenal Hyperplasia, Congenital - diagnosis Adrenal Hyperplasia, Congenital - therapy Adrenocorticotropic Hormone Birth Weight Gestational Age Humans Infant, Newborn Infant, Premature - blood Infant, Premature, Diseases - blood Infant, Premature, Diseases - diagnosis Infant, Premature, Diseases - therapy Reference Values Treatment Outcome
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Zusammenfassung:	This study investigated the use of corrected 17-alpha-hydroxyprogesterone (17-OHP) values to detect congenital adrenal hyperplasia (CAH) in newborn infants. 17-OHP concentrations in blood spots from 913 neonates were measured using a neonatal screening test. A prematurity index was calculated using a scoring system based on gestational age and birth weight. Blood spot 17-OHP concentrations divided by the sum of prematurity scores were defined as the corrected 17-OHP values. Preterm infants (
ISSN:	1550-8080