Efficacy and effectiveness of five day treatment of uncomplicated falciparum with artemisinin or artesunate in Vietnam
A study on efficacy and effectiveness of artemisinin (total dose of 60 mg/kg) and artesunate (total dose of 12 mg/kg over five days) in treatment of uncomplicated malaria was conducted in highly malaria transmitted areas in Vietnam. 126 uncomplicated malaria cases finished 14 day follow-up. 100% cur...
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| Veröffentlicht in: | Southeast Asian journal of tropical medicine and public health 1999-03, Vol.30 (1), p.3-6 |
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| container_title | Southeast Asian journal of tropical medicine and public health |
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| creator | Le, N B Pham, T Y Nguyen, B N Dang, C T Pham, T L Le, D C |
| description | A study on efficacy and effectiveness of artemisinin (total dose of 60 mg/kg) and artesunate (total dose of 12 mg/kg over five days) in treatment of uncomplicated malaria was conducted in highly malaria transmitted areas in Vietnam. 126 uncomplicated malaria cases finished 14 day follow-up. 100% cure rate achieved at day 14 in patients of the efficacy groups received either artemisinin or artesunate, while it was 83% and 93% in patients treated respectively with artemisinin and artesunate of the effectiveness groups. Compliance of the treatment regimens was discussed. |
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Compliance of the treatment regimens was discussed.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antimalarials - pharmacology</subject><subject>Antimalarials - therapeutic use</subject><subject>Antiparasitic agents</subject><subject>Artemisinins</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Drug Monitoring - methods</subject><subject>Female</subject><subject>Fever - parasitology</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Lactones - pharmacology</subject><subject>Lactones - therapeutic use</subject><subject>Malaria, Falciparum - blood</subject><subject>Malaria, Falciparum - complications</subject><subject>Malaria, Falciparum - drug therapy</subject><subject>Malaria, Falciparum - parasitology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pharmacology. 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Antiinfectious agents. Antiparasitic agents</topic><topic>Antimalarials - pharmacology</topic><topic>Antimalarials - therapeutic use</topic><topic>Antiparasitic agents</topic><topic>Artemisinins</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Drug Monitoring - methods</topic><topic>Female</topic><topic>Fever - parasitology</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Lactones - pharmacology</topic><topic>Lactones - therapeutic use</topic><topic>Malaria, Falciparum - blood</topic><topic>Malaria, Falciparum - complications</topic><topic>Malaria, Falciparum - drug therapy</topic><topic>Malaria, Falciparum - parasitology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pharmacology. Drug treatments</topic><topic>Sesquiterpenes - pharmacology</topic><topic>Sesquiterpenes - therapeutic use</topic><topic>Treatment Outcome</topic><topic>Tropical medicine</topic><topic>Vietnam</topic><toplevel>online_resources</toplevel><creatorcontrib>Le, N B</creatorcontrib><creatorcontrib>Pham, T Y</creatorcontrib><creatorcontrib>Nguyen, B N</creatorcontrib><creatorcontrib>Dang, C T</creatorcontrib><creatorcontrib>Pham, T L</creatorcontrib><creatorcontrib>Le, D C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Southeast Asian journal of tropical medicine and public health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Le, N B</au><au>Pham, T Y</au><au>Nguyen, B N</au><au>Dang, C T</au><au>Pham, T L</au><au>Le, D C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy and effectiveness of five day treatment of uncomplicated falciparum with artemisinin or artesunate in Vietnam</atitle><jtitle>Southeast Asian journal of tropical medicine and public health</jtitle><addtitle>Southeast Asian J Trop Med Public Health</addtitle><date>1999-03</date><risdate>1999</risdate><volume>30</volume><issue>1</issue><spage>3</spage><epage>6</epage><pages>3-6</pages><issn>0125-1562</issn><coden>SJTMAK</coden><abstract>A study on efficacy and effectiveness of artemisinin (total dose of 60 mg/kg) and artesunate (total dose of 12 mg/kg over five days) in treatment of uncomplicated malaria was conducted in highly malaria transmitted areas in Vietnam. 126 uncomplicated malaria cases finished 14 day follow-up. 100% cure rate achieved at day 14 in patients of the efficacy groups received either artemisinin or artesunate, while it was 83% and 93% in patients treated respectively with artemisinin and artesunate of the effectiveness groups. 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| identifier | ISSN: 0125-1562 |
| ispartof | Southeast Asian journal of tropical medicine and public health, 1999-03, Vol.30 (1), p.3-6 |
| issn | 0125-1562 |
| language | eng |
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| source | MEDLINE; EZB-FREE-00999 freely available EZB journals |
| subjects | Adolescent Adult Antibiotics. Antiinfectious agents. Antiparasitic agents Antimalarials - pharmacology Antimalarials - therapeutic use Antiparasitic agents Artemisinins Biological and medical sciences Child Drug Monitoring - methods Female Fever - parasitology Follow-Up Studies Humans Lactones - pharmacology Lactones - therapeutic use Malaria, Falciparum - blood Malaria, Falciparum - complications Malaria, Falciparum - drug therapy Malaria, Falciparum - parasitology Male Medical sciences Pharmacology. Drug treatments Sesquiterpenes - pharmacology Sesquiterpenes - therapeutic use Treatment Outcome Tropical medicine Vietnam |
| title | Efficacy and effectiveness of five day treatment of uncomplicated falciparum with artemisinin or artesunate in Vietnam |
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