To expedite or not to expedite ... That is the question

Summary Expedited review is usually conducted by the IRB chairperson or by 1 or more experienced IRB members designated by the IRB chairperson. An expedited reviewer will refer any research protocol that the reviewer would have disapproved to the full IRB committee for review. Whether expedited or full board review is warranted, it is imperative that all studies are of sound scientific design. Risks should always be reasonable in relation to whatever benefit can be expected. Participant selection must be equitable. Privacy and confidentiality should be maintained to the greatest degree possible. Subjects must be made aware that their participation is always voluntary, without undue coercion or influence, and they have a right to withdraw at any time. The bottom line is that whether the study can undergo expedited review, the same regulatory and ethical principles apply. And the answer to the question is still “If it meets the federal requirements for expedited review, the IRB will consider it.”