Multifocal Granulomatous Hepatitis Caused by Actinobacillus pleuropneumoniae Serotype 2 in Slaughter Pigs

In a survey of 66 894 slaughter pigs, 11 animals from three farms were found to have multifocal granulomatous lesions in the liver, caused by Actinobacillus pleuropneumoniae serotype 2. The lesions consisted of epithelioid cells and multinucleated giant cells, with asteroid bodies and discernible gr...

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Veröffentlicht in:	Journal of comparative pathology 2008-08, Vol.139 (2), p.61-66
Hauptverfasser:	Ohba, T., Shibahara, T., Kobayashi, H., Takashima, A., Nagoshi, M., Osanai, R., Kubo, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinobacillus Infections - pathology Actinobacillus Infections - veterinary Actinobacillus pleuropneumoniae Animals asteroid body bacterial infection Granuloma - microbiology Granuloma - pathology granulomatous hepatitis Hepatitis, Animal - microbiology Hepatitis, Animal - pathology Immunohistochemistry pig Pleuropneumonia - pathology Pleuropneumonia - veterinary porcine pneumonia Spleen - pathology Swine Swine Diseases - microbiology Swine Diseases - pathology
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Beschreibung
Zusammenfassung:	In a survey of 66 894 slaughter pigs, 11 animals from three farms were found to have multifocal granulomatous lesions in the liver, caused by Actinobacillus pleuropneumoniae serotype 2. The lesions consisted of epithelioid cells and multinucleated giant cells, with asteroid bodies and discernible gram-negative bacteria. Lymph nodes and spleen were occasionally affected. The results suggested that haematogenous spread had occurred from pre-existing pulmonary infections.
ISSN:	0021-9975 1532-3129
DOI:	10.1016/j.jcpa.2008.04.003