Convenient Synthesis of 3-Alkoxy-3-aryloxindoles by Intramolecular Arylation of Mandelic Amides

Medicinally important 3-alkoxy-3-aryloxindoles are conveniently prepared by the rapid microwave-promoted palladium-catalyzed intramolecular enolate arylation of mandelate-derived anilides.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of organic chemistry 2008-08, Vol.73 (16), p.6459-6461
Hauptverfasser:	Hillgren, J. Mikael, Marsden, Stephen P
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides - chemistry Benzene Derivatives - chemistry Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with only one n hetero atom and condensed derivatives Indoles - chemical synthesis Mandelic Acids - chemistry Organic chemistry Preparations and properties
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Beschreibung
Zusammenfassung:	Medicinally important 3-alkoxy-3-aryloxindoles are conveniently prepared by the rapid microwave-promoted palladium-catalyzed intramolecular enolate arylation of mandelate-derived anilides.
ISSN:	0022-3263 1520-6904
DOI:	10.1021/jo8010842