Hemoglobin Adducts and Mercapturic Acid Excretion of Acrylamide and Glycidamide in One Study Population

The aim of this study was to determine the relationship between the oxidative and reductive metabolic pathways of acrylamide (AA) in the nonsmoking general population. For the first time both the blood protein adducts and the urinary metabolites of AA and glycidamide (GA) were quantified in an espec...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2008-08, Vol.56 (15), p.6061-6068
Hauptverfasser:	Hartmann, Eva C., Boettcher, Melanie I., Schettgen, Thomas, Fromme, Hermann, Drexler, Hans, Angerer, Jürgen
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcysteine - urine Acrylamide Acrylamide - administration & dosage Acrylamide - blood Acrylamide - urine acrylamides Adolescent Adult adults Aged Aged, 80 and over Aging amino acid composition biochemical pathways Biological and medical sciences blood chemistry body weight Child children daily intake Diet dietary exposure dosage Epoxy Compounds - blood Epoxy Compounds - urine excretion Female Food industries Food toxicology Fundamental and applied biological sciences. Psychology gender differences glycidamide hemoglobin hemoglobin adducts Hemoglobins - chemistry human exposure human metabolism Humans Male mercapturic acid mercapturic acids metabolites Middle Aged oxidation Oxidation-Reduction quantitative analysis reduction toxicokinetics Valine - blood Valine - chemistry
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