GC-MS analysis of fatty acids in phospholipids from Chlorella vulgaris cultivated synchronously in the presence of propranolol

Changes in the content and composition of fatty acids in phospholipids were determined to estimate the effect of propranolol on the growth of unicellular green algae Chlorella vulgaris cultivated synchronously. The general biological activity of the cells and the division coefficient (DC) as well as...

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Veröffentlicht in:	Acta Poloniae pharmaceutica 1999-01, Vol.56 (1), p.21-27
Hauptverfasser:	Lodowska, J, Mazurek, U, Kurkiewicz, S, Wilczok, A, Swierczek, G, Tam, I, Pytel, A, Wilczok, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Arrhythmia Agents - pharmacology Cell Cycle - drug effects Cell Cycle - physiology Chlorella - chemistry Chlorella - drug effects Chromatography, Gas Fatty Acids - analysis Mass Spectrometry Membrane Lipids - analysis Phospholipids - analysis Propranolol - pharmacology
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Zusammenfassung:	Changes in the content and composition of fatty acids in phospholipids were determined to estimate the effect of propranolol on the growth of unicellular green algae Chlorella vulgaris cultivated synchronously. The general biological activity of the cells and the division coefficient (DC) as well as the cell synchronisation were disturbed by propranolol in a concentration dependent manner. Also, the effect of propranolol on the fatty acids content of Chlorella vulgaris phospholipids was proportional to its concentration.
ISSN:	0001-6837