Antiviral activity of some Nigerian medicinal plant extracts

Plants from Northern Nigeria with a history of use in both human and veterinary traditional medicine have been investigated for their antiviral activity and their cytotoxicity determined. Extracts were tested against poliovirus, astrovirus, herpes simplex viruses and parvovirus, using the microtitre...

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Veröffentlicht in:	Journal of ethnopharmacology 1999-12, Vol.68 (1), p.289-294
Hauptverfasser:	Kudi, A.C, Myint, S.H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral Antiviral Agents - pharmacology Biological and medical sciences Caco-2 Cells - physiology Cytotoxicity General pharmacology Haplorhini human traditional medicines Humans In Vitro Techniques Kidney - physiology Mamastrovirus - drug effects Medical sciences medicinal plants Medicine, Traditional Microchemistry Nigeria Parvovirus - drug effects Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant extract plant extracts Plant Extracts - pharmacology Poliovirus - drug effects Simplexvirus - drug effects Traditional medicine veterinary drugs veterinary traditional medicines
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Beschreibung
Zusammenfassung:	Plants from Northern Nigeria with a history of use in both human and veterinary traditional medicine have been investigated for their antiviral activity and their cytotoxicity determined. Extracts were tested against poliovirus, astrovirus, herpes simplex viruses and parvovirus, using the microtitre plate inhibition tests. Most of the extracts have activity against more than one virus at a dose rate of between 100 and 400 μg/100 μl.
ISSN:	0378-8741 1872-7573
DOI:	10.1016/S0378-8741(99)00049-5