Association between apolipoprotein E polymorphism and Alzheimer's disease in Koreans

We analyzed the aplolipoprotein E (APOE) genotypes of 110 probable AD patients and 226 cognitively normal controls in Koreans. The APOE ε4 allele was more prevalent in both early- and late-onset AD patients (P

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Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience letters 1999-12, Vol.277 (3), p.145-148
Hauptverfasser:	Kim, Ki Woong, Jhoo, Jin Hyeong, Lee, Kang Uk, Lee, Dong Young, Lee, Jung Hie, Youn, Ji Youn, Lee, Byeong Jae, Han, Sul Hee, Woo, Jong Inn
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Age of Onset Age-at-onset Aged Aged, 80 and over Alzheimer Disease - epidemiology Alzheimer Disease - genetics Alzheimer's disease Apolipoprotein E Apolipoprotein E4 Apolipoproteins E - genetics Asian Continental Ancestry Group - genetics Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Gene Frequency Genotype Heterozygote Homozygote Humans Korea - ethnology Koreans Male Medical sciences Middle Aged Neurology Polymorphism, Genetic - physiology Reference Values Risk Sex Sex Characteristics
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Beschreibung
Zusammenfassung:	We analyzed the aplolipoprotein E (APOE) genotypes of 110 probable AD patients and 226 cognitively normal controls in Koreans. The APOE ε4 allele was more prevalent in both early- and late-onset AD patients (P
ISSN:	0304-3940 1872-7972
DOI:	10.1016/S0304-3940(99)00867-8