Birth weight affects final height in patients treated for growth hormone deficiency

OBJECTIVE Birth weight influences both postnatal growth and the initial response to GH therapy in GH‐deficient subjects, but its relationship to final height is uncertain. Therefore, we examined final height results in a group of subjects treated for GH deficiency who were born small, appropriate or...

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Veröffentlicht in:	Clinical endocrinology (Oxford) 1999-12, Vol.51 (6), p.733-739
Hauptverfasser:	Cacciari, E., Zucchini, S., Cicognani, A., Pirazzoli, P., Balsamo, A., Salardi, S., Cassio, A., Pasini, A., Gualandi, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Biological and medical sciences Birth Weight Body Height - drug effects Child Child, Preschool Female Growth Disorders - drug therapy Growth Hormone - blood Growth Hormone - deficiency Hormones. Endocrine system Human Growth Hormone - therapeutic use Humans Linear Models Male Medical sciences Pharmacology. Drug treatments Retrospective Studies
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Zusammenfassung:	OBJECTIVE Birth weight influences both postnatal growth and the initial response to GH therapy in GH‐deficient subjects, but its relationship to final height is uncertain. Therefore, we examined final height results in a group of subjects treated for GH deficiency who were born small, appropriate or large for gestational age (GA). DESIGN Retrospective study. PATIENTS 108 GH‐treated patients (age at diagnosis 11.1 ± 2.0 years) affected by idiopathic and isolated GH deficiency (peak
ISSN:	0300-0664 1365-2265
DOI:	10.1046/j.1365-2265.1999.00875.x