Peptides crossing the blood–brain barrier: some unusual observations

An interactive blood–brain barrier (BBB) helps regulate the passage of peptides from the periphery to the CNS and from the CNS to the periphery. Many peptides cross the BBB by simple diffusion, mainly explained by their lipophilicity and other physicochemical properties. Other peptides cross by satu...

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Veröffentlicht in:	Brain research 1999-11, Vol.848 (1-2), p.96-100
Hauptverfasser:	Kastin, Abba J., Pan, Weihong, Maness, Lawrence M., Banks, William A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood-Brain Barrier - physiology Blood–brain barrier Cerebral circulation. Blood-brain barrier. Choroid plexus. Cerebrospinal fluid. Circumventricular organ. Meninges Diffusion Fundamental and applied biological sciences. Psychology Humans neuropeptides Peptide Peptides - metabolism Saturable transport Vertebrates: nervous system and sense organs
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