Antipsychotics for aggressive behaviour: no better than placebo for non-psychotic adults with learning difficulties

Patients: 86 adults with intellectual disability (intelligence quotient =2 episodes of aggressive behaviour, modified overt aggression scale (MOAS) score >=4 in past 7 days), but who had not received a clinical diagnosis of psychosis. First-line treatments with strong evidence of efficacy should be used such as altering environmental supports and provision of psychological and behavioural therapies. 4