Microfluidic based single cell microinjection

We report a microfluidic based approach for single cell microinjection in which fluid streams direct a cell onto a fixed microneedle in contrast to moving a microneedle towards an immobilized cell, as done in conventional methods. The approach simplifies microinjection and offers the potential for f...

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Veröffentlicht in:Lab on a chip 2008, Vol.8 (8), p.1258-1261
Hauptverfasser: Adamo, Andrea, Jensen, Klavs F
Format: Artikel
Sprache:eng
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Zusammenfassung:We report a microfluidic based approach for single cell microinjection in which fluid streams direct a cell onto a fixed microneedle in contrast to moving a microneedle towards an immobilized cell, as done in conventional methods. The approach simplifies microinjection and offers the potential for flow through automated microinjection of cells.
ISSN:1473-0197
1473-0189
DOI:10.1039/b803212b