Uptake of testing for BRCA1 2 mutations in South East Scotland

We investigated the uptake of genetic testing by 54 families in South East Scotland with a BRCA1/2 mutation. At a median of 37 months since identification of the mutation, the overall rate of uptake of testing in 269 eligible family members was 32%. First-degree relatives were significantly (P

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Bibliographische Detailangaben
Veröffentlicht in:	European journal of human genetics : EJHG 2008-08, Vol.16 (8), p.906-912
Hauptverfasser:	HOLLOWAY, Susan M, BERNHARD, Birgitta, CAMPBELL, Harry, LAM, Wayne W. K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences BRCA1 protein BRCA1 Protein - genetics BRCA2 Protein - genetics Breast cancer Breast Neoplasms - genetics Breast Neoplasms - psychology Children Family Female Fundamental and applied biological sciences. Psychology General aspects. Genetic counseling Genetic Counseling Genetic counselling Genetic Predisposition to Disease Genetic screening Genetic testing Genetic Testing - psychology Genetic Testing - utilization Genetics of eukaryotes. Biological and molecular evolution Germ-Line Mutation - genetics Humans Male Medical genetics Medical sciences Molecular and cellular biology Mutation Ovarian cancer Scotland Socio-economic aspects Womens health
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	We investigated the uptake of genetic testing by 54 families in South East Scotland with a BRCA1/2 mutation. At a median of 37 months since identification of the mutation, the overall rate of uptake of testing in 269 eligible family members was 32%. First-degree relatives were significantly (P
ISSN:	1018-4813 1476-5438
DOI:	10.1038/ejhg.2008.17