Membrane Chromatography: Preparation and Applications to Protein Separation

As a result of the convective flow of solutes through porous membranes, membrane chromatography has a higher capture efficiency and a higher productivity than column chromatography and shows most promising industrial applications for the recovery, isolation, and purification of proteins and enzymes. This paper presents a comprehensive review of the methods for preparation of adsorptive membranes (such as surface modification, in situ copolymerization, direct formation from hydrophilic materials, and functionalized particulate‐entrapped membranes) and deals particularly with novel macroporous chitin and chitosan membranes for protein separations developed by the authors.