Recurrent benign intrahepatic cholestasis and their progression to familiar progressive intrahepatic cholestasis

Benign recurrent intrahepatic cholestasis (BRIC) is a rare form of intrahepatic cholestasis characterized by repeated self-limited episodes of severe pruritus and jaundice. Classically its natural evolution is benign, without progress to fibrosis or hepatic insufficiency; although, lastly were reported cases which progress to Progressive familial intrahepatic cholestasis (PFIC). This disease is characterized by progressive hepatic insufficiency and cirrhosis. We present the case of a 32 years old male patient who went to Gastroenterology Service of Arzobispo Loayza National Hospital by pruritus and jaundice. We reported this case for its infrequent presentation and because is an entity which should be considered within differential diagnosis of hepatic cholestasis diseases.