The impact of ganciclovir-resistant cytomegalovirus infection after lung transplantation

Cytomegalovirus (CMV) resistance to ganciclovir has become increasingly common in acquired immunodeficiency syndrome patients but has only rarely been reported in recipients of solid organ transplants. A retrospective study of ganciclovir susceptibility testing of CMV isolates recovered from lung tr...

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Veröffentlicht in:	Transplantation 1999-11, Vol.68 (9), p.1272-1279
Hauptverfasser:	KRUGER, R. M, SHANNON, W. D, ARENS, M. Q, LYNCH, J. P, STORCH, G. A, TRULOCK, E. P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged AIDS/HIV Antilymphocyte Serum - therapeutic use Antiviral Agents - therapeutic use Biological and medical sciences Cytomegalovirus Infections - drug therapy Drug Resistance, Microbial Female ganciclovir Ganciclovir - therapeutic use Graft Rejection human cytomegalovirus Humans Lung Transplantation - adverse effects Lung Transplantation - mortality Male Medical sciences Middle Aged Retrospective Studies Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the respiratory system T-Lymphocytes - immunology
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Beschreibung
Zusammenfassung:	Cytomegalovirus (CMV) resistance to ganciclovir has become increasingly common in acquired immunodeficiency syndrome patients but has only rarely been reported in recipients of solid organ transplants. A retrospective study of ganciclovir susceptibility testing of CMV isolates recovered from lung transplant recipients was performed. Patients with CMV isolates having partial (1
ISSN:	0041-1337 1534-6080
DOI:	10.1097/00007890-199911150-00010