Immunologic Properties Differ in Preterm Infants Fed Olive Oil vs Soy-Based Lipid Emulsions During Parenteral Nutrition

Background: In the first period of life, premature infants need parenteral nutrition. Lipid emulsions (LEs), which are a part of parenteral nutrition, are known as potent immunological modulators and may therefore influence the immune status of parenterally fed infants. The aim of the study was to c...

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Veröffentlicht in:	JPEN. Journal of parenteral and enteral nutrition 2008-07, Vol.32 (4), p.448-453
Hauptverfasser:	Gawecka, Agnieszka, Michalkiewicz, Jacek, Kornacka, Maria Katarzyna, Luckiewicz, Barbara, Kubiszewska, Iza
Format:	Artikel
Sprache:	eng
Schlagworte:	cytokine Double-Blind Method Fat Emulsions, Intravenous - administration & dosage Fat Emulsions, Intravenous - chemistry Female Humans Infant Nutritional Physiological Phenomena - immunology Infant, Newborn - immunology Infant, Premature - immunology Interleukin-10 - biosynthesis Interleukin-6 - biosynthesis Leukocytes, Mononuclear - immunology Leukocytes, Mononuclear - secretion Male Olive Oil parenteral nutrition Parenteral Nutrition - methods Plant Oils premature infant Soybean Oil Treatment Outcome Tumor Necrosis Factor-alpha - biosynthesis
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Zusammenfassung:	Background: In the first period of life, premature infants need parenteral nutrition. Lipid emulsions (LEs), which are a part of parenteral nutrition, are known as potent immunological modulators and may therefore influence the immune status of parenterally fed infants. The aim of the study was to compare tumor necrosis factor (TNF)-α, interleukin (IL)-6, and IL-10 production in the peripheral blood mononuclear cells (PBMCs) of premature infants parenterally fed with 2 LEs: olive oil (OO) and soybean oil (SO). Methods: Premature infants born at
ISSN:	0148-6071 1941-2444
DOI:	10.1177/0148607108319802