Predictive factors for delayed graft function (DGF) and its impact on renal graft survival in children: A report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS)

: We define delayed graft function (DGF) as the need for dialysis during the first post‐transplant week. We analyzed 5272 transplants, of which 2486 were of living donor (LD) and 2786 were of cadaver donor (CD) origin. Twelve per cent (620/5272) of all patients developed DGF. Donor specific rates we...

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Veröffentlicht in:Pediatric transplantation 1999-11, Vol.3 (4), p.293-300
Hauptverfasser: Tejani, Amir H., Sullivan, E. Kenneth, Alexander, Steven R., Fine, Richard N., Harmon, William E., Kohaut, Edward C.
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Sprache:eng
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Zusammenfassung:: We define delayed graft function (DGF) as the need for dialysis during the first post‐transplant week. We analyzed 5272 transplants, of which 2486 were of living donor (LD) and 2786 were of cadaver donor (CD) origin. Twelve per cent (620/5272) of all patients developed DGF. Donor specific rates were 5.6% for LD and 19.1% for CD patients. Factors predictive of DGF in CD patients were: African‐American race (25%), prolonged cold ischemia (24%), absence of T‐cell induction antibody therapy and absence of HLA‐DR matching. The relative risk (RR) for graft failure due to DGF was 6.02 (p
ISSN:1397-3142
1399-3046
DOI:10.1034/j.1399-3046.1999.00057.x