Meiosis: Rec8 is the reason for cohesion

During meiosis, sister chromatids produced by chromosome duplication are held together by Rec8, a meiosis-specific cohesion protein. Rec8 joins the whole length of the sister chromatids together, and, as meiosis proceeds, is lost in a stepwise manner that correlates with the loss of sister-chromatid...

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Veröffentlicht in:	Nature cell biology 1999-09, Vol.1 (5), p.E125-E127
Hauptverfasser:	Stoop-Myer, Chatanika, Amon, Angelika
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Cancer Research Cell Biology Chromatids - genetics Chromatids - ultrastructure Developmental Biology Drosophila Fungal Proteins - physiology Life Sciences Meiosis - physiology Mitosis Models, Genetic news-and-views Phosphoproteins Saccharomyces cerevisiae - cytology Saccharomyces cerevisiae - physiology Schizosaccharomyces - cytology Schizosaccharomyces - physiology Schizosaccharomyces pombe Proteins Stem Cells
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Beschreibung
Zusammenfassung:	During meiosis, sister chromatids produced by chromosome duplication are held together by Rec8, a meiosis-specific cohesion protein. Rec8 joins the whole length of the sister chromatids together, and, as meiosis proceeds, is lost in a stepwise manner that correlates with the loss of sister-chromatid cohesion.
ISSN:	1465-7392 1476-4679
DOI:	10.1038/12956