Ghrelin in Pathological Conditions

The recently identified gastric hormone ghrelin was initially described as a natural Growth Hormone Secretagogue Receptor ligand. Apart from ghrelin's first discovered action, which was the stimulation of Growth Hormone release, implications for many other functions have been reported. It seems...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	ENDOCRINE JOURNAL 2008, Vol.55(3), pp.439-453
Hauptverfasser:	KATERGARI, Simoni A., MILOUSIS, Athanasios, PAGONOPOULOU, Olga, ASIMAKOPOULOS, Byron, NIKOLETTOS, Nikos K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bariatric Surgery Cardiovascular Physiological Phenomena Cardiovascular System - metabolism Cardiovascular System - pathology Diabetes Mellitus - etiology Disease - etiology Feeding and Eating Disorders - etiology Ghrelin Ghrelin - physiology Growth Disorders - etiology Growth Hormone - deficiency Growth Hormone - metabolism Humans Liver - pathology Liver - physiology Neoplasms - etiology Obesity - etiology Obesity - surgery Pathological conditions Renal Insufficiency - etiology Thyroid Diseases - etiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The recently identified gastric hormone ghrelin was initially described as a natural Growth Hormone Secretagogue Receptor ligand. Apart from ghrelin's first discovered action, which was the stimulation of Growth Hormone release, implications for many other functions have been reported. It seems that ghrelin exhibits an important role in conditions related to processes regulating nutrition, body composition and growth, as well as heart, liver, thyroid or kidney dysfunction. In this review, current available knowledge about ghrelin's role in various pathological conditions is presented.
ISSN:	0918-8959 1348-4540
DOI:	10.1507/endocrj.K07-106