A comparison of two indirect methods for estimating average levels of gene flow using microsatellite data

A comparison of two indirect methods for estimating average levels of gene flow using microsatellite data

We compare the performance of Nm estimates based on FST and RST obtained from microsatellite data using simulations of the stepwise mutation model with range constraints in allele size classes. The results of the simulations suggest that the use of microsatellite loci can lead to serious overestimat...

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Veröffentlicht in:Molecular ecology 1999-09, Vol.8 (9), p.1513-1520
Hauptverfasser: Gaggiotti, O. E., Lange, O., Rassmann, K., Gliddon, C.
Format: Artikel
Sprache:eng
Schlagworte:
Alleles
Animals
gene flow
genetic differentiation
Genetics, Population
Microsatellite Repeats
microsatellites
Models, Genetic
Monte Carlo Method
Mutation
RST
Sample Size
Selection Bias
stepwise mutation model
subdivided populations
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Zusammenfassung:We compare the performance of Nm estimates based on FST and RST obtained from microsatellite data using simulations of the stepwise mutation model with range constraints in allele size classes. The results of the simulations suggest that the use of microsatellite loci can lead to serious overestimations of Nm, particularly when population sizes are large (N > 5000) and range constraints are high (K 
ISSN:0962-1083
1365-294X
DOI:10.1046/j.1365-294x.1999.00730.x