Mytilus edulis histone gene clusters containing only H1 genes

We isolated five different phage clones containing histone gene clusters with up to five H1 genes per phage clone from a Mytilus edulis genomic library. Among these H1 genes, nine gene types coding for five different H1 proteins have been identified. All H1 histone genes were located on repetitive r...

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Veröffentlicht in:	Journal of molecular evolution 1999-11, Vol.49 (5), p.645-655
Hauptverfasser:	Drabent, B, Kim, J S, Albig, W, Prats, E, Cornudella, L, Doenecke, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Bacteriophage lambda - genetics Base Sequence Bivalvia - genetics Chromatin Cloning, Molecular Dinucleotide Repeats DNA - genetics Eukaryotes Evolution, Molecular Evolutionary biology Gene Duplication Genomic Library Genomics Histones - genetics Molecular Sequence Data Multigene Family Proteins Restriction Mapping Sequence Homology, Amino Acid Sequence Homology, Nucleic Acid
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Zusammenfassung:	We isolated five different phage clones containing histone gene clusters with up to five H1 genes per phage clone from a Mytilus edulis genomic library. Among these H1 genes, nine gene types coding for five different H1 proteins have been identified. All H1 histone genes were located on repetitive restriction fragments with only slightly different sizes. The H1 coding regions show highly related sequences, suggesting that the multitude of H1 genes has evolved by gene duplication events. Core histone genes could not be found on these five Mytilus edulis genome fragments.
ISSN:	0022-2844 1432-1432
DOI:	10.1007/PL00006585