Limitations of clinical diagnosis in acute stroke

Limitations of clinical diagnosis in acute stroke

Trials in acute stroke have recruited on the basis of clinical diagnosis. Using MRI we have shown that clinical diagnosis is more limited than previously appreciated, thus trials may have been underpowered or confounded.

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Bibliographische Detailangaben
Veröffentlicht in:The Lancet (British edition) 1999-10, Vol.354 (9189), p.1523-1523
Hauptverfasser: Allder, SJ, Moody, AR, Martel, AL, Morgan, PS, Delay, GS, Gladman, JR, Fentem, P, Lennox, GG
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Clinical trials
Clinical Trials as Topic - statistics & numerical data
Confounding Factors (Epidemiology)
Diagnostic Errors - statistics & numerical data
Humans
Investigative techniques, diagnostic techniques (general aspects)
Medical diagnosis
Medical sciences
Nervous system
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Stroke
Stroke - diagnosis
Stroke - drug therapy
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Beschreibung
Zusammenfassung:Trials in acute stroke have recruited on the basis of clinical diagnosis. Using MRI we have shown that clinical diagnosis is more limited than previously appreciated, thus trials may have been underpowered or confounded.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(99)04360-3