Primary Antiphospholipid Syndrome with Moyamoya-Like Vascular Changes

We describe a young girl with antiphospholipid syndrome (APS) and moyamoya-like cerebrovascular changes which reversed after anticoagulation. Although there was a risk of hemorrhage from collateral vessels, we speculate that this treatment may have prevented progression of the vascular abnormalities...

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Veröffentlicht in:	Pediatric neurosurgery 1999-07, Vol.31 (1), p.45-48
Hauptverfasser:	Booth, Frances, Yanofsky, Rochelle, Ross, Ian B., Lawrence, Patrick, Oen, Kiem
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Anticardiolipin - blood Anticoagulants - therapeutic use Antiphospholipid Syndrome - blood Antiphospholipid Syndrome - complications Antiphospholipid Syndrome - drug therapy Antiphospholipid Syndrome - pathology Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Case Report Cerebral Angiography Child Female Humans Medical sciences Moyamoya Disease - complications Moyamoya Disease - diagnostic imaging Moyamoya Disease - drug therapy Moyamoya Disease - pathology Pharmacology. Drug treatments Space life sciences Stroke - complications Warfarin - therapeutic use
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Zusammenfassung:	We describe a young girl with antiphospholipid syndrome (APS) and moyamoya-like cerebrovascular changes which reversed after anticoagulation. Although there was a risk of hemorrhage from collateral vessels, we speculate that this treatment may have prevented progression of the vascular abnormalities, while resolution of the thrombus resulted in improved cerebrovascular circulation.
ISSN:	1016-2291 1423-0305
DOI:	10.1159/000028830