Intraoperative Intraarterial Urokinase in Early Postoperative Stroke Following Carotid Endarterectomy: A Useful Adjunct

Intraoperative Intraarterial Urokinase in Early Postoperative Stroke Following Carotid Endarterectomy: A Useful Adjunct

The purpose of this study was to determine the efficacy of intraoperative intraarterial urokinase (UK) in patients who suffered an acute stroke immediately following carotid endarterectomy (CEA). From January 1995 to March 1998, 823 carotid endarterectomies were performed. The subsequent results sho...

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Veröffentlicht in:Annals of vascular surgery 1999-11, Vol.13 (6), p.566-570
Hauptverfasser: Winkelaar, Gerrit B., Salvian, Anthony J., Fry, Peter D., Reid, John D.S., Teal, Philip A., Taylor, David C., Hsiang, York N.
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Carotid Artery, Internal
Combined Modality Therapy
Endarterectomy, Carotid - adverse effects
Female
Humans
Infusions, Intra-Arterial
Intraoperative Care
Male
Middle Aged
Plasminogen Activators - administration & dosage
Retrospective Studies
Stroke - drug therapy
Stroke - etiology
Stroke - surgery
Thrombolytic Therapy
Urokinase-Type Plasminogen Activator - administration & dosage
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Zusammenfassung:The purpose of this study was to determine the efficacy of intraoperative intraarterial urokinase (UK) in patients who suffered an acute stroke immediately following carotid endarterectomy (CEA). From January 1995 to March 1998, 823 carotid endarterectomies were performed. The subsequent results showed that intraarterial UK in the setting of early post-CEA neurologic events appears to be safe and may be a useful adjunct to re-exploration in improving neurologic outcomes.
ISSN:0890-5096
1615-5947
DOI:10.1007/s100169900299