TNF-α and chronic fatigue syndrome

Based upon the clinical presentation of chronic fatigue syndrome (CFS), we hypothesized that proinflammatory cytokines may play a role in the pathogenesis of the disease. We therefore undertook a retrospective cross-sectional study to examine the role of TNF-alpha in patients with CFS. Our results s...

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Veröffentlicht in:	Journal of clinical immunology 1999-09, Vol.19 (5), p.314-316
Hauptverfasser:	MOSS, R. B, MERCANDETTI, A, VOJDANI, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Cross-Sectional Studies Fatigue Syndrome, Chronic - blood Fatigue Syndrome, Chronic - immunology Female Humans Male Medical sciences Middle Aged Nervous system involvement in other diseases. Miscellaneous Neurology Retrospective Studies Tumor Necrosis Factor-alpha - metabolism
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Zusammenfassung:	Based upon the clinical presentation of chronic fatigue syndrome (CFS), we hypothesized that proinflammatory cytokines may play a role in the pathogenesis of the disease. We therefore undertook a retrospective cross-sectional study to examine the role of TNF-alpha in patients with CFS. Our results suggest a significant increase serum TNF-alpha in patients with CFS (P
ISSN:	0271-9142 1573-2592
DOI:	10.1023/A:1020595709352