The effect of aggressive and moderate lowering of LDL-cholesterol and low dose anticoagulation on plasma lipids, apolipoproteins and lipoprotein families in post coronary artery bypass graft trial

The effect of aggressive and moderate lowering of LDL-cholesterol and low dose anticoagulation on plasma lipids, apolipoproteins and lipoprotein families in post coronary artery bypass graft trial

The reported results (The Post Coronary Artery Bypass Graft Trial Investigators. The effect of aggressive lowering of low-density lipoprotein cholesterol levels and low-dose anticoagulation on obstructive changes in saphenous-vein coronary-artery bypass grafts. New Engl J Med 1997;336:153–162) of th...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Atherosclerosis 1999-10, Vol.146 (2), p.369-379
Hauptverfasser: Alaupovic, Petar, Fesmire, Jim D., Hunnighake, Donald, Domanski, Michael, Forman, Sandra, Knatterud, Genell L., Forrester, James, Herd, J.Alan, Hoogwerf, Byron, Campeau, Lucien, Gobel, Fredarick L.
Format: Artikel
Sprache:eng
Schlagworte:
Anticholesteremic Agents - therapeutic use
Anticoagulants - therapeutic use
Apolipoproteins
Apolipoproteins - blood
Apolipoproteins E - blood
Apolipoproteins E - genetics
Arteriosclerosis - blood
Arteriosclerosis - complications
Arteriosclerosis - therapy
Atherosclerosis
Biological and medical sciences
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Coronary Artery Bypass
Coronary Disease - surgery
Disease Progression
Double-Blind Method
Female
General and cellular metabolism. Vitamins
Graft Occlusion, Vascular - blood
Graft Occlusion, Vascular - etiology
Graft Occlusion, Vascular - prevention & control
Humans
Lipids
Lipids - blood
Lipoprotein families
Lipoproteins, VLDL - blood
Lovastatin
Male
Medical sciences
Middle Aged
Pharmacology. Drug treatments
Saphenous Vein - transplantation
Saphenous vein grafts
Treatment Outcome
Triglycerides - blood
Warfarin
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The reported results (The Post Coronary Artery Bypass Graft Trial Investigators. The effect of aggressive lowering of low-density lipoprotein cholesterol levels and low-dose anticoagulation on obstructive changes in saphenous-vein coronary-artery bypass grafts. New Engl J Med 1997;336:153–162) of the Post Coronary Artery Bypass Graft (Post CABG) trial have shown that aggressive lowering was more effective than moderate lowering of low density lipoprotein (LDL) cholesterol in reducing the progression of atherosclerosis in saphenous-vein grafts (27 vs. 39%; P
ISSN:0021-9150
1879-1484
DOI:10.1016/S0021-9150(99)00151-3