Filaggrin variants confer susceptibility to asthma

[...]this study has only 50% power to detect the primary effect size of 1.8. [...]the likelihood of this replicating the primary observation was as likely to fail as it was to succeed.

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of allergy and clinical immunology 2008-05, Vol.121 (5), p.1294-1295
Hauptverfasser:	McLean, W. H. Irwin, PhD, DSc, Palmer, Colin N.A., PhD, Henderson, John, MD, Kabesch, Michael, MD, Weidinger, Stephan, MD, Irvine, Alan D., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Asthma - genetics Eczema Genetic Predisposition to Disease Genotype & phenotype Humans Hypersensitivity, Immediate - genetics Intermediate Filament Proteins - genetics Mutation Studies
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	[...]this study has only 50% power to detect the primary effect size of 1.8. [...]the likelihood of this replicating the primary observation was as likely to fail as it was to succeed.
ISSN:	0091-6749 1097-6825
DOI:	10.1016/j.jaci.2008.02.039