Feasibility of combined use of intravascular ultrasound radiofrequency data analysis and optical coherence tomography for detecting thin-cap fibroatheroma

Feasibility of combined use of intravascular ultrasound radiofrequency data analysis and optical coherence tomography for detecting thin-cap fibroatheroma

Aims To evaluate the feasibility of the combined use of virtual histology (VH)-intravascular ultrasound (IVUS) and optical coherence tomography (OCT) for detecting in vivo thin-cap fibroatheroma (TCFA). Methods and results In 56 patients with angina, 126 plaques identified by IVUS findings were anal...

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Veröffentlicht in:European heart journal 2008-05, Vol.29 (9), p.1136-1146
Hauptverfasser: Sawada, Takahiro, Shite, Junya, Garcia-Garcia, Hector M., Shinke, Toshiro, Watanabe, Satoshi, Otake, Hiromasa, Matsumoto, Daisuke, Tanino, Yusuke, Ogasawara, Daisuke, Kawamori, Hiroyuki, Kato, Hiroki, Miyoshi, Naoki, Yokoyama, Mitsuhiro, Serruys, Patrick W., Hirata, Ken-ichi
Format: Artikel
Sprache:eng
Schlagworte:
Acute Coronary Syndrome - etiology
Aged
Angina Pectoris - etiology
Biological and medical sciences
Cardiology. Vascular system
Coronary Angiography
Coronary Artery Disease - diagnosis
Feasibility Studies
Female
Humans
Male
Medical sciences
Necrosis - pathology
Necrotic core
Observer Variation
OCT
Pilot Projects
Statistics as Topic
Thin-cap fibroatheroma
Tomography, Optical Coherence - methods
Ultrasonography, Interventional - methods
Vessel positive remodelling
VH-IVUS
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Zusammenfassung:Aims To evaluate the feasibility of the combined use of virtual histology (VH)-intravascular ultrasound (IVUS) and optical coherence tomography (OCT) for detecting in vivo thin-cap fibroatheroma (TCFA). Methods and results In 56 patients with angina, 126 plaques identified by IVUS findings were analysed using both VH-IVUS and OCT. IVUS-derived TCFA was defined as an abundant necrotic core (>10% of the cross-sectional area) in contact with the lumen (NCCL) and %plaque-volume >40%. OCT-derived TCFA was defined as a fibrous cap thickness of
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/ehn132