Risk of Guillain-Barré Syndrome following Serogroup C Meningococcal Conjugate Vaccine in Quebec, Canada

To assess the risk of Guillain-Barré syndrome (GBS) following administration of meningococcal serogroup C-CRM197 conjugate vaccine, provincial immunization records were linked with hospital discharge records, and medical charts were reviewed. In the cohort of 1.9 million individuals (age, 2 months t...

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Veröffentlicht in:	Clinical infectious diseases 2008-04, Vol.46 (8), p.e75-e77
Hauptverfasser:	De Wals, Philippe, Deceuninck, Geneviève, Boucher, Renée-Myriam, Ouakki, Manale
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Child Child, Preschool Cohort Studies Guillain-Barre Syndrome - diagnosis Guillain-Barre Syndrome - epidemiology Guillain-Barre Syndrome - etiology Humans Infant Meningococcal Vaccines - administration & dosage Meningococcal Vaccines - adverse effects Neisseria meningitidis Quebec - epidemiology
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Beschreibung
Zusammenfassung:	To assess the risk of Guillain-Barré syndrome (GBS) following administration of meningococcal serogroup C-CRM197 conjugate vaccine, provincial immunization records were linked with hospital discharge records, and medical charts were reviewed. In the cohort of 1.9 million individuals (age, 2 months to 20 years), observed postvaccination frequencies of GBS were not higher than expected.
ISSN:	1058-4838 1537-6591
DOI:	10.1086/533469